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ischaemic heart disease

Practice targeted AMC-style multiple-choice questions on ischaemic heart disease.

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A 45-year-old male with poorly controlled diabetes mellitus and ischaemic heart disease, living in a rural Indigenous community, presents with fevers, cough, lethargy, night sweats, and occasional hemoptysis. What is the most appropriate initial investigation for suspected tuberculosis in this patient if he is unable to produce sputum spontaneously?

A. Interferon-Gamma Release Assay (IGRA)
B. Sputum GeneXpert
C. Try hypertonic saline to get sputum.
D. CT chest
E. Empirical anti-TB treatment
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An 80-year-old man with known severe COPD and stable ischaemic heart disease presents to the emergency department with a 2-day history of worsening shortness of breath, increased cough productive of yellow sputum, and ankle swelling. He is usually independent but now struggles to walk across a room. On examination: Alert but distressed. BP 130/85 mmHg, HR 110 bpm, RR 28 breaths/min, Temp 37.8°C, SpO2 88% on room air. Chest examination reveals diffuse wheezes and crackles bilaterally, reduced air entry at the bases. JVP is elevated to 5 cm above the sternal angle. Mild pitting edema to the knees. ECG shows sinus tachycardia, no acute ischaemic changes. Chest X-ray shows hyperinflation, flattened diaphragms, increased bronchial markings, and mild interstitial prominence. Given this presentation, what is the most appropriate initial management step?

A. Administer controlled oxygen therapy aiming for SpO2 88-92% and nebulised bronchodilators.
B. Administer intravenous broad-spectrum antibiotics.
C. Perform urgent echocardiogram.
D. Administer intravenous furosemide.
E. Administer high-flow oxygen via non-rebreather mask.
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